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. 2017 Jul 21;7:6171. doi: 10.1038/s41598-017-06275-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Venn diagrams representing differentially expressed genes (DEG) through T. cruzi infection with or without DMS treatment. (A) Comparison between DEG after 25 h (Tc 1 h condition) or 48 h (Tc 24 h condition) after T. cruzi infection with respect to uninfected macrophages (CTR condition). (B) Analysis of common DEG by DMS treatment for 1 h (DMS 1 h) and 24 h (DMS 24 h) when compared to infected macrophages. (C) Comparison between DEG by T. cruzi infection with or without 1 h DMS treatment with respect to uninfected macrophages. (D) Comparison between DEG during 48 h infection with or without 24 h DMS treatment with respect to uninfected macrophages. (*) indicates genes with |FC| ≥ 2 but p-values > 0.05.