Table 1.

The target HBV sequences and the possible off-target sequences in the host genome.

Site name	Sequence
HBc-1	CCCTAGAAGAAGAACTCCCTCGC
Off-target #1–1	CCTTAGAAGAAGAACTTGCCCGA
Off-target #1–2	CCCTAGAAGAAGAACTCCATTTT
Off-target #1–3	CCCTAGAAGAAGAACTCACCATT
HBc-2	GTCGCAGAAGATCTCAATCTCGG
Off-target #2–1	ATTCACTAAGATCTCAATCTCGG
Off-target #2–2	ACAAGGGAAGATCTCAATCTGGG
Off-target #2–3	GGAAGACAAGATCTCAATCTGGG

Underlining indicates the difference between the targeted HBV sequences and the candidate off-target sequences.