Table 2.
Frequency of mutations induced by Cas9, nickase-Cas9 and d-Cas9 with a pair of sgRNAs.
| Nuclease | Total read (count) | Indels mutations (count) | Mutation frequency (%) |
|---|---|---|---|
| Cas9 | 45210 | 25258 | 55.87 |
| nickase-Cas9 | 44110 | 17210 | 39.02 |
| d-Cas9 | 41938 | 86 | 0.21 |
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