IgM responses against Salmonella Typhi antigens in a Bangladeshi cohort of febrile patients and controls. Boxplots showing IgM measurements (optical density) in plasma from afebrile controls (light gray), febrile patients with an infection other than typhoid fever (medium gray), and confirmed typhoid patients (dark gray). Dark horizontal lines represent the mean IgM measurement, with the box representing the 25th and 75th percentiles, whiskers represent the 5th and 95th percentiles; outliers are represented by dots. A) Boxplots of antibody responses against (from left to right and upper to lower) STY0452, STY0769, STY1086, STY1372, STY1612, STY1522, STY1703, STY1767, STY3208, and STY4190. All mean antibody measurements were statistically significant between the healthy controls and typhoid infections and between other infections and typhoid infections, with the exception of STY1522 (p < 0.05 Wilcoxon Rank sum). B) Boxplots of antibody responses against (in order) STY4539, STY1886, Vi. All mean antibody measurements are statistically significant between the healthy controls and typhoid infections and between other infections and typhoid infections (p < 0.05 Wilcoxon Rank sum).