Table 3.

The sensitivity and specificity of multiple antigens for typhoid diagnosis using blood culture positive patients only as positive reference group (n = 19).

Antigen combinations	STY1886 & Vi	STY4190 & STY1886 & Vi	STY4539 & STY4190 & STY1886 & Vi
Specificity	0.88	0.89	0.88
Sensitivity	0.84	0.84	0.89
Number with undiagnosed febrile disease predicted to have typhoid (n = 226)	119 (52%)	78 (34%)	71 (31%)
Number with clinically suspected typhoid disease predicted to have typhoid (n = 18)	15 (83%)	13 (72%)	13 (72%)
AUC (95%CI)	0.859 (0.746, 0.972)	0.891 (0.791, 0.991)	0.912 (0.81, 1.014)