Figure 2.

Pharmacological Inhibition of Forelimb Primary Motor Cortex Disrupts Triggered Reaching Behavior

(A) For one example mouse, peristimulus time histograms of reach onset timing aligned on the vibrotactile trigger onset (black triangle) in five conditions (from left to right): (1) baseline, (2) muscimol in primary visual cortex (V1), (iii) Ringer’s solution in M1, (4) muscimol in M1 causing a reduction in timed reaches, and (5) recovery of reach timing.

(B) Population analysis (five mice) of hit proportion in trials with a vibrotactile trigger stimulus (black), and false-positives in trials without stimulus (gray). ^∗p < 0.05 (Wilcoxon).

(C) Proportion of trials in which the mouse initiated a timed reach movement, including trials without contact to the target sensor.

(D) Proportion of ready trials in which the paw was on the rest sensor during the 500 ms before the trigger.

See also Figure S2.