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. 2017 Jul 22;390(10092):363–373. doi: 10.1016/S0140-6736(16)32589-2

Table 4.

Sensitivity analyses

Fatigue (CFQ) Physical function (SF-36 PF)
Strict intention-to-treat analysis
n 211 211
Mean difference compared with control group (95% CI) −4·0 (−5·9 to −2·1) 6·3 (1·8 to 10·9)
p value <0·0001 0·006
Therapist effect
n 199 199
Mean difference compared with control group (95% CI) −4·1 (−5·4 to −2·8) 6·3 (2·7 to 9·9)
p value <0·0001 0·001
Met CDC criteria
n 138 141
Mean difference compared with control group (95% CI) −4·1 (−6·5 to −1·7) 6·3 (1·1 to 11·6)
p value 0·001 0·019
Met Oxford criteria
n 156 159
Mean difference compared with control group (95% CI) −3·5 (−5·7 to −1·3) 5·6 (0·8 to 10·4)
p value 0·002 0·024
Adjustment for covariates*
n 199 199
Mean difference compared with control group (95% CI) −4·3 (−6·3 to −2·4) 6·9 (2·2 to 11·6)
p value <0·0001 0·004

CFQ=Chalder Fatigue Questionnaire. SF-36 PF=Short-Form 36 physical function subscale. CDC=US Centers For Disease Control and Prevention.

*

Adjusted for age, sex, ethnic origin, study centre, education level, employment status, high SF-36 PF (≥45), high depression (≥11), high anxiety (≥11), and baseline International Physical Activity Questionnaire Scores (low, medium, or high).