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a The mRNA expression of CYP1B1 quantified by RT-PCR and normalized to β-actin as a housekeeping gene. N = 6; mean ± SEM. b CYP1B1 catalytic activity determined by MROD assay. N = 3; mean ± SEM. c CYP1B1 catalytic activity determined by EROD assay. N = 3; mean ± SEM. *P < 0.05 compared to doxorubicin, +P < 0.05 compared to control
