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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Exp Hematol. 2017 May 4;52:65–71. doi: 10.1016/j.exphem.2017.04.011

Fig. 4.

Fig. 4

Effects of buthionine sulfoximine (BSO) on GSH concentration, ROS production, cell survival, and expression of drug transporters. J45.01 cells were incubated with BSO for 48 hrs and the level of cellular GSH (A), cell survival (C), and changes in the expression of drug transporters (D) were determined. Early changes in the level of ROS were determined in J45.01 cells exposed to BSO for 24 hrs (B). The results are averages±SD (A, B, C) or a representative (D) of three independent experiments.