Table 1.
Top 20 upregulated and downregulated circRNAs between sham-operated and CCI rats (sham vs CCI)
| CircRNA | Fold change | Best_transcript | Gene symbol | Raw intensity (CCI) | Raw intensity (sham) |
|---|---|---|---|---|---|
| Top 20 upregulated in CCI | |||||
| rno_circRNA_013779 | 28.8 | NM_001108050 | Smek1 | 721 | 34 |
| rno_circRNA_008008 | 11.3 | XM_002728604 | Nup133 | 1,517 | 139 |
| rno_circRNA_003724 | 10.0 | XM_222205 | RGD1309762 | 1,257 | 128 |
| rno_circRNA_016355 | 9.5 | NM_021752 | Birc2 | 1,451 | 158 |
| rno_circRNA_008646 | 9.3 | NM_001107689 | Ash1l | 3,225 | 333 |
| rno_circRNA_011054 | 9.0 | – | – | 598 | 73 |
| rno_circRNA_004560 | 8.7 | NM_001100971 | RGD1305110 | 818 | 104 |
| mmu_circRNA_33592 | 8.6 | NM_024486 | Acvr1 | 978 | 122 |
| rno_circRNA_007702 | 8.1 | NM_001039713 | Fto | 4,271 | 489 |
| rno_circRNA_001285 | 8.0 | NM_001107604 | Pdcd11 | 452 | 66 |
| rno_circRNA_001148 | 7.9 | NM_001107608 | Hectd2 | 1,410 | 178 |
| rno_circRNA_017183 | 7.9 | NM_001191067 | Tbc1d8 | 3,889 | 467 |
| rno_circRNA_017427 | 7.7 | NM_021687 | Erbb4 | 1,301 | 174 |
| rno_circRNA_009685 | 7.7 | ENSRNOT00000071477 | Mcu | 1,158 | 155 |
| rno_circRNA_007108 | 7.6 | NM_001107398 | Wdr33 | 582 | 85 |
| rno_circRNA_008973 | 7.4 | NM_017041 | Ppp3ca | 7,358 | 1,001 |
| rno_circRNA_013293 | 7.4 | NM_001107954 | Reck | 6,935 | 946 |
| mmu_circRNA_000043 | 7.3 | NM_001271502 | Ctnnd2 | 995.5 | 145 |
| rno_circRNA_014649 | 7.3 | NM_001169103 | Crim1 | 2,379 | 329 |
| rno_circRNA_008686 | 7.1 | NM_012780 | Arnt | 1,541 | 218 |
| Top 20 downregulated in CCI | |||||
| rno_circRNA_007512 | −2.8 | NM_001106133 | Dym | 138 | 382 |
| rno_circRNA_007511 | −2.6 | NM_001106133 | Dym | 79 | 209 |
| rno_circRNA_014170 | −2.6 | NM_001012191 | Dtnb | 272 | 703 |
| rno_circRNA_016819 | −2.6 | ENSRNOT00000021758 | Fert2 | 63 | 156 |
| rno_circRNA_007514 | −2.6 | NM_001106133 | Dym | 90 | 228 |
| rno_circRNA_007419 | −2.5 | NM_001107382 | Zfp532 | 1,450 | 3,259 |
| rno_circRNA_006343 | −2.5 | NM_031339 | Parg | 110 | 275 |
| rno_circRNA_014174 | −2.5 | NM_001012191 | Dtnb | 272 | 666 |
| rno_circRNA_009879 | −2.5 | NM_133300 | Ddx39b | 517 | 1,220 |
| rno_circRNA_006094 | −2.5 | NM_001107312 | Mtmr7 | 1,476 | 3,233 |
| rno_circRNA_014172 | −2.5 | NM_001012191 | Dtnb | 245 | 589 |
| rno_circRNA_014166 | −2.5 | NM_001012191 | Dtnb | 195 | 473 |
| rno_circRNA_011941 | −2.5 | NM_030844 | Ica1 | 188 | 458 |
| rno_circRNA_002862 | −2.5 | NM_001100502 | Gbe1 | 39 | 78 |
| rno_circRNA_004376 | −2.4 | NM_138538 | Dnm3 | 48 | 107 |
| rno_circRNA_007562 | −2.4 | XM_225744 | Setbp1 | 505 | 1,157 |
| rno_circRNA_007421 | −2.3 | NM_001107382 | Zfp532 | 872 | 1,939 |
| rno_circRNA_013991 | −2.3 | NM_021767 | Nrxn1 | 496.5 | 1,112 |
| mmu_circRNA_45374 | −2.3 | XM_002730185 | Kdm6a | 76 | 177 |
| rno_circRNA_001650 | −2.3 | NM_001191947 | Dact3 | 327 | 764 |
Abbreviations: circRNAs, circular RNAs; CCI, chronic constriction injury.