Table III.
Changes in other observations.*
| Observation | Baseline | At 3 mo | At 12 mo |
|---|---|---|---|
| Body weight, kg | 65.5 (13.7) | 64.9 (13.3) | 65.3 (13.7) |
| Systolic blood pressure, mm Hg | 129.5 (16.2) | 127.1 (13.4) | 127.4 (13.4) |
| Diastolic blood pressure, mm Hg† | 76.6 (11.2) | 74.2 (9.7) | 74.2 (10.2) |
| Pulse rate, bpm | 74.9 (13.6) | 73.6 (12.8) | 73.1 (11.1) |
| Total cholesterol level, mg/dL† | 200.1 (37.4) | 196.2 (41.1) | 192.4 (36.0) |
| LDL cholesterol level, mg/dL | 111.8 (30.2) | 107.8 (26.4) | 111.2 (27.5) |
| HDL cholesterol level, mg/dL† | 54.4 (13.9) | 53.9 (13.8) | 53.5 (14.1) |
| Triglyceride level, mg/dL | 166.0 (92.4) | 157.3 (90.6) | 152.4 (87.2) |
| Aspartate aminotransferase level, U/L | 26.1 (13.1) | 25.2 (11.8) | 25.2 (10.8) |
| Alanine aminotransferase level, U/L | 30.2 (21.6) | 28.0 (18.2) | 27.3 (17.2) |
| γ-glutamyltranspeptidase level, U/L | 53.4 (67.8) | 50.6 (64.8) | 49.2 (72.6) |
| Total bilirubin level, mg/dL | 0.7 (0.4) | 0.6 (0.2) | 0.7 (0.4) |
| Blood urea nitrogen level, mg/dL | 15.9 (5.1) | 16.0 (4.9) | 16.4 (5.8) |
| Creatinine level, mg/dL† | 0.77 (0.23) | 0.78 (0.23) | 0.80 (0.25) |
| Uric acid level, mg/dL† | 5.2 (1.3) | 5.6 (1.3) | 5.5 (1.3) |
⁎
Data are presented as mean (SD).
†
P < 0.05 compared with baseline, after 3 months, and at 12 months as determined by 1-way repeated measures ANOVA.