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. 2017 Apr 10;84:42–49. doi: 10.1016/j.curtheres.2017.04.001

Table I.

Study* designs.

Population n Dose Sampling plan Basic pharmokinetic model Reference
Japanese 13 women, 21 men 14 g ethanol (350 mL beer)10 min in the fasted state 5, 10, 20, 30, 60 min postdose 1 compartment 11
Chinese 36 women, 31 men 36 and 56 g ethanol 1.5, 2, 2.5, 3, 1 compartment 10
Indian 43 women, 44 men 200 and 300 mL (mixture of vodka and orange juice) 1 h with a meal 3.25, 3.5, 3.75, 4, 4.25, 4.5, 4.75, 5, 6 h postdose Michaelis-Menten elimination

The current dataset for reanalysis was obtained from study described in reference 11; the priors for population pharmacokinetic parameters were obtained from reference.10

Dose for women.

Dose for men.