Table 2.
Biochemical assay | IC50 Hdm2 ± SD (nM)a | |
---|---|---|
1a | cis | 0.15 ± 0.04 |
1b | trans | 0.19 ± 0.05 |
2a | cis | 0.17 ± 0.06 |
2b | trans | 0.23 ± 0.08 |
3 | linear 1 | 0.45 ± 0.05 |
4 | linear 2 | 0.46 ± 0.08 |
Nutlin‐3a | – | 8.0 ± 1.5 |
Means ±SD from at least three independent experiments.