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. Author manuscript; available in PMC: 2018 Jun 6.
Published in final edited form as: Circulation. 2017 Mar 29;135(23):2288–2298. doi: 10.1161/CIRCULATIONAHA.116.025390

Fig. 3. Lack of VEGFR3 in endothelial cells attenuates BMP signaling in mice.

Fig. 3

(A) Localization of YFP expression driven by the Vegfr3 promoter to the endothelial layer of bismuth contrast filled pulmonary arteriole. Scale bar = 50 μm. (B) Reduced pSMAD 1/5 levels in lung homogenates from Vegfr3 ECKO mice compared to lung homogenates from control littermates. (C) pSMAD 1/5 to total SMAD 5 ratio in control littermates and Vegfr3 ECKO mice. (D) Quantification of Id2 expression to GAPDH ratio in control and Vegf3 ECKO mice. *P < 0.05, **P < 0.01.