Table 2.
Comparison of early and late HD groups according to the RIFLE and AKIN classifications
| Parameters | All patients (N=68) | Early HD (according to RIFLE) 17 (25%) | Late HD (according to RIFLE) 51 (75%) | P value | Early HD (according to AKIN) 27 (39,7%) | Late HD (according to AKIN) 41 (60,3%) | P value |
|---|---|---|---|---|---|---|---|
| Age (y) (median, interquartile range) | 66.5 (54-76.8) | 58 (39.5-70.5) | 68 (57-78) | 0,062 | 64 (44-72) | 70 (57.5-79) | 0.114 |
| Gender (male, %) | 39 (56.5) | 8 (47.1) | 31 (60.8) | 0.322 | 14 (51.9) | 25 (61) | 0.617 |
| Length of ICU stay (d) (median, interquartile range) | 10.5 (5-21) | 6 (2-16) | 14 (6-26) | 0.008 | 7 (3-12) | 15 (7.5-27.5) | 0.002 |
| APACHE II (median, interquartile range) | 24 (18.3-28) | 24 (17-33) | 24 (19-28) | 0.580 | 25 (18-31) | 23 (19-28) | 0.411 |
| SOFA score (median, interquartile range) | 7 (5-11) | 6 (4-6) | 8 (5-11) | 0.216 | 7 (4-10) | 8 (5-11) | 0.293 |
| Reasons for admission to the ICU (n, %) | |||||||
| Respiratory insufficiency | 46 (67.6) | 11 (64.7) | 35 (68.6) | 0.772 | 18 (66.7) | 28 (68.3) | 1.000 |
| Sepsis/septic shock | 46 (67.6) | 9 (52.9) | 37 (72.5) | 0.148 | 17 (63) | 29 (70.7) | 0.599 |
| Cardiovascular | 10 (14.7) | 1 (5.9) | 9 (17.6) | 0.236 | 4 (14.8) | 6 (14.6) | 0.984 |
| Gastrointestinal | 16 (23.5) | 3 (17.6) | 13 (25.5) | 0.509 | 6 (22.2) | 10 (24.4) | 0.837 |
| Renal | 28 (41.2) | 11 (64.7) | 17 (33.3) | 0.044 | 14 (51.9) | 14 (34.1) | 0.208 |
| Comorbidities (n, %) | |||||||
| Diabetes mellitus | 19 (28) | 4 (23.5) | 15 (29.4) | 0.640 | 6 (22.2) | 13 (31.7) | 0.425 |
| Cardiovascular | 27 (39.7) | 4 (23.5) | 23 (45.1) | 0.156 | 9 (33.3) | 18 (43.9) | 0.453 |
| Hypertension | 32 (47.1) | 6 (35.3) | 26 (51) | 0.401 | 9 (33.3) | 23 (56.1) | 0.085 |
| Cancer | 30 (44.1) | 9 (52.9) | 21 (41.2) | 0.415 | 13 (48.1) | 17 (41.5) | 0.625 |
| Respiratory (chronic obstructive lung diseases) | 13 (19.1) | 4 (23.5) | 9 (17.6) | 0.593 | 6 (22.2) | 7 (17.1) | 0.754 |
| Gastrointestinal | 8 (11.8) | 2 (11.8) | 6 (11.8) | 0.844 | 3 (11.1) | 5 (12.2) | 0.705 |
| Neurological | 11 (16.2) | 1 (5.9) | 10 (19.6) | 0.183 | 2 (7.4) | 9 (22) | 0.111 |
| Mechanical ventilation during HD (n, %) | 52 (76.5) | 9 (52.9) | 43 (84.3) | 0.018 | 18 (66.7) | 34 (82.9) | 0.150 |
| Sepsis during HD (n, %) | 60 (88.2) | 14 (82.4) | 46 (90.2) | 0.385 | 22 (81.5) | 38 (92.7) | 0.161 |
| Mortality in the ICU (n, %) | 9 (52.9) | 46 (90.2) | 0.001 | 18 (66.7) | 37 (90.2) | 0.026 |
HD: Hemodialysis; ICU: Intensive care unit; APACHE II Score: Acute physiology and chronic health evaluation II score; SOFA Score: Sequential organ failure assessment score; RIFLE, Risk, Injury, Failure, Loss, and End-stage renal failure; AKIN: Acute Kidney Injury Network