Table 3.
Total and differential cell counts at baseline and the standard mean difference (SMD) in cell counts between intervention group and placebo group after treatment.
| Source | Total cells | Neutrophils | Lymphocytes | Eosinophils | Macrophages | |||||
| Number (× 104/mL) | SMD (95% CI) | Number (× 104/mL) | SMD (95% CI) | Number (× 104/mL) | SMD (95% CI) | Number (× 104/mL) | SMD (95% CI) | Number (× 104/mL) | SMD (95% CI) | |
| Yildiz [22] | 350.0 | -0.6 (-1.6 to 0.4) | 260.0 | -2.2 (-3.4 to -1.0) | 3.5 | -0.5 (-1.4 to 0.5) | 7.0 | -1.1 (-2.1 to -0.1) | 80.0 | 0.2 (-0.5 to 0.9) |
| Confalonieri [20] | 219.0 | -0.4 (-1.1 to 0.3) | 158.8 | -3.4 (-4.5 to -2.3) | 6.6 | -0.5 (-1.2 to 0.2) | 6.2 | -0.6 (-1.3 to 0.1) | 45.0 | -0.3 (-0.9 to 0.3) |
| Mirici [21] | 196.5 | -1.0 (-1.7 to -0.3) | 146.5 | -7.5 (-9.3 to -5.6) | 1.6 | -0.7 (-1.4 to -0.1) | 1.6 | 0.2 (-0.4 to 0.8) | 38.2 | 0.5 (-0.5 to 1.5) |
| Sugiura [7] | 165.7 | 0.2 (-0.8 to 1.2) | 102.9 | 0.1 (-0.9 to 1.1) | 6.1 | 0.04 (-0.9 to 1.0) | 4.5 | -0.2 (-1.2 to 0.8) | 52.0 | -0.3 (-1.1 to 0.5) |
| Culpitt [19] | 165.0 | -0.3 (-1.1 to 0.5) | 145.0 | -0.4 (-1.2 to 0.4) | NR | NR | NR | NR | 25.0 | -0.2 (-0.9 to 0.6) |
| Keatings [18] | 6.3* | -0.1 (-0.9 to 0.7) | 4.3* | -0.4 (-1.1 to 0.4) | 6.0* | 0.0 (-0.7 to 0.8) | 0.2* | -0.2 (-1.0 to 0.6) | 1.8* | 0.2 (-0.7 to 1.2) |
| Pooled Summary | -0.4 (-0.8 to -0.1) | -2.2 (-3.8 to -0.5) | -0.4 (-0.7 to -0.1) | -0.3 (-0.6 to 0.1) | -0.02 (-0.3 to 0.3) | |||||
* cell count/ml
Abbreviations: NR, not reported/not calculable.