Skip to main content
. Author manuscript; available in PMC: 2017 Jul 24.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 Jul-Aug;2(4):367–381. doi: 10.1002/wnan.86

FIGURE 1.

FIGURE 1

Nanopores in thin membranes used for single molecule detection. (a) A transmission electron image of a pore with a diameter of 2.2 nm in a 15-nm thick Si3N4 membrane. (b) A cross-section through a 2-nm nanopore in a silicon nitride membrane showing a dsDNA in the pore. (c) Distribution of the electrostatic potential in a nanopore at 2.6-V bias across the membrane in 1 M KCl. (d) A measurement of the electrolytic current through the 2.2-nm pore interacting with a λ-DNA with 1.0 V applied across the silicon nitride membrane. The current blockades are observed as DNA translocates through the pore. The figure on the right is an expanded view of a blockade. Figures (b) and (c) courtesy of A. Aksimentiev.