Skip to main content
. Author manuscript; available in PMC: 2017 Jul 24.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 Jul-Aug;2(4):367–381. doi: 10.1002/wnan.86

FIGURE 5.

FIGURE 5

(a) A transmission electron micrograph of a 2.3 × 2.0 nm nanopore in a 15-nm thick silicon nitride membrane. (b) Electrolytic current measured in 100 mM KCl at 800 mV (blue) and 200 mV through the pore shown in (a) as a function of time. The frequency of blockades decreases dramatically with voltage; at 200 mV (red) no transients are observed. (c) The frequency of blockades observed with the same pore as a function of membrane voltage illustrating the frequency drop as voltage decreases below 0.5 V. The dotted line represents a fit to the data. (d) Distributions illustrating the frequency as a function of the duration of a current blockade, tD, above threshold at 800 mV (red), 600 mV (black), and 400 mV (green). The distribution depends on the voltage. Inset: 1/tD as a function of the applied voltage indicating a threshold.