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Dose-dependent effects of the CC12 mixture on serum (a), urine (b), uric acid levels, and fractional excretion of uric acid (FEUA) (c) in PO-induced hyperuricemic rat. NC, normal control group; PO, potassium oxonate-induced hyperuricemia group; CC12, mixture of CF and CB at a ratio of 1 : 2; AP 10, 10 mg/kg allopurinol. Data are expressed as the mean ± SEM (n = 8). ##p < 0.01 and ###p < 0.01 versus the NC group; ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.01 versus the PO group.
