Table 2.
XOD activity of CF, CB, and CC12 mixture and their marker compounds.
| Sample treatment | Concentration (μg/ml) | % inhibition | IC50 (μg/ml) |
|---|---|---|---|
| CF | 100 | 5.3 ± 2.8 | >500 |
| 250 | 8.9 ± 4.1 | ||
| 500 | 39.2 ± 6.9 | ||
| CB | 100 | 31.2 ± 2.6 | 143 |
| 250 | 100.3 ± 3.1 | ||
| 500 | 98.4 ± 0.1 | ||
| CC12 mixture | 100 | 23.2 ± 0.4 | 153.8 |
| 250 | 94.3 ± 3.2 | ||
| 500 | 101.0 ± 0.2 | ||
| Chlorogenic acid | 62.5 | 24.0 ± 1.7 | 103.8 |
| 125 | 63.6 ± 1.5 | ||
| 250 | 107.3 ± 0.6 | ||
| 3,4-Dicaffeoylquinic acid | 62.5 | 21.0 ± 1.5 | 79.7 |
| 125 | 104.6 ± 2.6 | ||
| 250 | 85.0 ± 1.2 | ||
| Coumarin | 62.5 | 22.8 ± 0.1 | 95.2 |
| 125 | 75.1 ± 1.0 | ||
| 250 | 103.9 ± 0.7 | ||
| Cinnamaldehyde | 62.5 | 101.2 ± 3.2 | 43.7 |
| 125 | 126.3 ± 5.6 | ||
| 250 | 118.8 ± 35.1 | ||
| trans-Cinnamic acid | 62.5 | 54.3 ± 0.7 | 58.8 |
| 125 | 96.7 ± 1.9 | ||
| 250 | 114.9 ± 0.4 | ||
| o-Methoxycinnamaldehyde | 62.5 | 104.7 ± 0.2 | 25.7 |
| 125 | 101.2 ± 0.2 | ||
| 250 | 100.0 ± 0.4 | ||
| Allopurinol | 6.25 | 51.7 ± 0.7 | |
| 12.5 | 71.7 ± 0.1 | ||
| 25 | 80.3 ± 0.3 |
Chrysanthemum indicum Linne flower ethanol extract; CB, Cinnamomum cassia (L.) J. Persl bark ethanol extract; CC, mixture of CF and CB. Data are expressed as the mean ± SEM.