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. 2017 Jul 9;2017:1721434. doi: 10.1155/2017/1721434

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Copyright © 2017 Ni Zeng et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

BDNF attenuated myocardial oxidative stress in septic shock rats that was abolished by L-NAME. (a and b) Visualization and quantitation of 4-HNE in heart tissue. (c) Superoxide dismutase (SOD) activity in heart tissue. (d) Free 15-F2t-isoprostane in heart tissue was measured by using an enzyme-linked immunoassay kit. Data are mean ± SEM, with n = 8 animals per group. ^∗P < 0.05 versus sham; ^#P < 0.05 versus CLP; ^&P < 0.05 versus CLP + rhBDNF. CLP: cecal ligation and puncture; rhBDNF: recombined BDNF protein.