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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Front Neuroendocrinol. 2017 May 11;46:15–31. doi: 10.1016/j.yfrne.2017.05.001

Figure 2. Cytoplasmic interactions between GR and NFκB cascades.

Figure 2

The co-chaperone FKBP5 has been identified as a binding partner to multiple proteins constituting the NFκB pathway including TAK1, IKKα, and p65. Furthermore, the chaperone proteins CDC37, Hsp90, and Hsc70 also bind IKKα and p65. The functional significance of these protein-protein interactions remain incompletely understood.