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Modulation of collagen synthesis in the heart after administration of MSC. Representative images of Sirius red stained heart sections of T. cruzi infected mice administered with saline (a), MSC-WT (b), or MSC-Gal3KD (c). (d) Quantification of the collagen-stained area by morphometry. (e) Type I collagen (Col1a1) gene expression analysis by qRT-PCR in the heart tissue. ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001; #P = 0.01, compared to the other groups.
