Table 4.
Hematological values of rats after 28-day exposure of nano-sized Nd2O3
| Parameter | Dose (mg/m3) | |||
|---|---|---|---|---|
|
| ||||
| 0 | 0.5 | 2.5 | 10 | |
| No. of animals examined | 8 | 8 | 8 | 8 |
| RBC (106/μL) | 8.40 ± 0.41a | 8.69 ± 0.30 | 8.82 ± 0.60 | 8.58 ± 0.51 |
| Hemoglobin (g/dL) | 15.1 ± 0.71 | 15.7 ± 0.48 | 15.8 ± 0.65 | 15.4 ± 0.63 |
| Hematocrit (%) | 42.3 ± 1.63 | 43.8 ± 1.49 | 44.2 ± 1.97 | 42.7 ± 1.80 |
| MCV (fL) | 50.4 ± 1.04 | 50.4 ± 1.63 | 50.2 ± 1.50 | 49.8 ± 1.37 |
| MCH (pg) | 18.0 ± 0.55 | 18.1 ± 0.60 | 17.9 ± 0.56 | 17.9 ± 0.70 |
| MCHC (g/dL) | 35.7 ± 0.51 | 35.8 ± 0.25 | 35.6 ± 0.35 | 36.5 ± 0.96 |
| RDW (%) | 12.4 ± 0.76 | 12.1 ± 0.46 | 11.9 ± 0.68 | 12.9 ± 2.04 |
| Platelet (103/μL) | 925 ± 121 | 987 ± 113 | 772 ± 157 | 984 ± 51.4 |
| MPV (fL) | 9.16 ± 0.66 | 8.91 ± 0.49 | 8.85 ± 0.74 | 9.76 ± 1.68 |
| WBC (103/μL) | 3.90 ± 1.20 | 4.82 ± 0.85 | 4.49 ± 2.31 | 4.08 ± 1.65 |
| Neutrophils (103/μL) | 0.79 ± 0.29 | 0.99 ± 0.25 | 1.08 ± 0.61 | 0.78 ± 0.21 |
| Lymphocytes (103/μL) | 2.97 ± 1.01 | 3.65 ± 0.70 | 3.22 ± 1.68 | 3.12 ± 1.42 |
| Monocytes (103/μL) | 0.06 ± 0.03 | 0.08 ± 0.03 | 0.10 ± 0.07 | 0.09 ± 0.04 |
| Eosinophils (103/μL) | 0.05 ± 0.04 | 0.06 ± 0.02 | 0.06 ± 0.02 | 0.05 ± 0.03 |
| Basophils (103/μL) | 0.01 ± 0.01 | 0.01 ± 0.01 | 0.01 ± 0.01 | 0.01 ± 0.01 |
RBC, red blood cell count; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red cell distribution width; MPV, mean platelet volume; WBC, white blood cell count.
a
Values are expressed as means ± SD.