Table 7.
Parameter | Dose (mg/m3) | |||
---|---|---|---|---|
| ||||
0 | 0.5 | 2.5 | 10 | |
No. of animals examined | 8 | 8 | 7 | 8 |
AST (IU/L) | 85.5 ± 9.79a | 83.8 ± 11.0 | 84.6 ± 11.5 | 92.3 ± 19.8 |
ALT (IU/L) | 54.1 ± 6.10 | 62.4 ± 15.0 | 63.3 ± 10.3 | 59.4 ± 9.73 |
ALP (IU/L) | 618 ± 140 | 617 ± 176 | 649 ± 189 | 604 ± 101 |
GGT (IU/L) | 0.99 ± 0.71 | 1.06 ± 0.49 | 1.21 ± 0.63 | 0.95 ± 0.45 |
CPK (IU/L) | 262 ± 134 | 274 ± 196 | 217 ± 135 | 203 ± 124 |
LDH (IU/L) | 910 ± 529 | 984 ± 796 | 718 ± 542 | 781 ± 568 |
TBil (mg/dL) | 0.10 ± 0.04 | 0.10 ± 0.04 | 0.10 ± 0.05 | 0.09 ± 0.03 |
Glucose (mg/dL) | 135 ± 15.8 | 125 ± 12.5 | 139 ± 17.7 | 130 ± 9.64 |
TCho (mg/dL) | 78.7 ± 16.9 | 75.1 ± 12.3 | 73.5 ± 12.1 | 64.1 ± 8.41 |
Triglyceride (mg/dL) | 48.2 ± 14.5 | 47.6 ± 12.7 | 40.4 ± 12.9 | 42.7 ± 11.9 |
TP (g/dL) | 7.26 ± 0.26 | 7.08 ± 0.30 | 7.31 ± 0.34 | 7.19 ± 0.25 |
Albumin (g/dL) | 4.75 ± 0.14 | 4.69 ± 0.18 | 4.76 ± 0.16 | 4.71 ± 0.15 |
BUN (mg/dL) | 21.2 ± 2.70 | 21.5 ± 3.92 | 20.4 ± 2.34 | 22.2 ± 3.90 |
Creatinine (mg/dL) | 0.51 ± 0.05 | 0.49 ± 0.04 | 0.51 ± 0.02 | 0.52 ± 0.02 |
IP (mg/dL) | 8.08 ± 0.93 | 8.11 ± 0.62 | 8.49 ± 0.83 | 7.95 ± 0.74 |
Ca++ (mg/dL) | 11.8 ± 0.66 | 11.2 ± 0.44 | 11.3 ± 0.44 | 11.0 ± 0.41 |
AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, gamma glutamyl transferase; CPK, creatine phosphokinase; LDH, lactate dehydrogenase; TBil, total bilirubin; TCho, total cholesterol; TP, total protein; BUN, blood urea nitrogen; IP, inorganic phosphorus; Ca, calcium.
Values are expressed as means ± SD.