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. 2017 Jul 15;33(3):239–253. doi: 10.5487/TR.2017.33.3.239

Table 8.

Absolute and relative organ weights of rats treated with nano-sized Nd2O3 for 28 days

Parameter (after exposure) Dose (mg/m3)

0 0.5 2.5 10
No. of animals examined 8 8 8 8
Body weight (g) 346.3 ± 18.53a 345.4 ± 21.98 359.2 ± 19.99 347.1 ± 19.53
Lung (g) 1.391 ± 0.094 2.141 ± 0.270** 2.345 ± 0.114** 2.238 ± 0.149**
 Per body weight (%) 0.402 ± 0.016 0.619 ± 0.059** 0.655 ± 0.047** 0.645 ± 0.034**
Liver (g) 9.395 ± 0.664 9.490 ± 0.867 9.843 ± 0.981 9.189 ± 0.585
 Per body weight (%) 2.713 ± 0.110 2.745 ± 0.124 2.735 ± 0.155 2.650 ± 0.149
Kidney (g) 2.325 ± 0.161 2.424 ± 0.142 2.456 ± 0.218 2.345 ± 0.118
 Per body weight (%) 0.672 ± 0.043 0.703 ± 0.043 0.683 ± 0.040 0.676 ± 0.032
Spleen (g) 0.651 ± 0.085 0.644 ± 0.060 0.657 ± 0.070 0.610 ± 0.072
 Per body weight (%) 0.188 ± 0.018 0.186 ± 0.011 0.183 ± 0.014 0.176 ± 0.021
Brain (g) 2.038 ± 0.084 2.006 ± 0.049 2.044 ± 0.094 1.981 ± 0.086
 Per body weight (%) 0.590 ± 0.033 0.583 ± 0.038 0.571 ± 0.041 0.572 ± 0.035

Parameter (after recovery) Dose (mg/m3)

0 0.5 2.5 10

No. of animals examined 8 8 7 8
Body weight (g) 499.9 ± 28.93 495.9 ± 25.25 464.6 ± 44.10 488.6 ± 30.07
Lung (g) 1.709 ± 0.132 2.118 ± 0.191** 3.077 ± 0.482** 3.495 ± 0.460**
 Per body weight (%) 0.342 ± 0.027 0.427 ± 0.030** 0.661 ± 0.063** 0.716 ± 0.082**
Liver (g) 13.75 ± 1.675 13.49 ± 0.918 12.39 ± 1.509 13.02 ± 1.021
 Per body weight (%) 2.745 ± 0.224 2.720 ± 0.144 2.664 ± 0.135 2.667 ± 0.151
Kidney (g) 3.071 ± 0.292 2.974 ± 0.173 2.829 ± 0.357 2.890 ± 0.148
 Per body weight (%) 0.614 ± 0.033 0.600 ± 0.033 0.610 ± 0.058 0.592 ± 0.029
Spleen (g) 0.926 ± 0.095 0.862 ± 0.116 0.828 ± 0.080 0.853 ± 0.034
 Per body weight (%) 0.185 ± 0.017 0.174 ± 0.021 0.178 ± 0.010 0.175 ± 0.013
Brain (g) 2.140 ± 0.098 2.113 ± 0.055 2.073 ± 0.072 2.066 ± 0.099
 Per body weight (%) 0.428 ± 0.014 0.427 ± 0.018 0.450 ± 0.049 0.425 ± 0.041
a

Values are expressed as means ± SD.

**

Significantly different from vehicle control at p<0.01.