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. 2017 Jan 9;6(1):e004903. doi: 10.1161/JAHA.116.004903

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© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Multivariable adjusted associations between carotid–femoral pulse wave velocity (CFPWV) and (A) global longitudinal strain (GLS) and (B) global circumferential strain (GCS). GLS was significantly worse (less negative) with greater CFPWV, and GCS was significantly worse (less negative) with greater CFPWV. Analyses were adjusted for key covariates: cohort, age, sex, height, weight, glucose, total/HDL cholesterol ratio, natural log‐triglycerides, diabetes mellitus, current smoker, antihypertensive medication use, lipid‐lowering medication use, heart rate, systolic blood pressure, augmentation index, left ventricular mass, left ventricular wall thickness, and left ventricular diastolic dimension. The symbol Δ refers to difference in GLS or GCS compared to the median per CFPWV value. CL indicates confidence limit; HDL, high‐density lipoprotein.