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. 2017 Jul 24;8:807. doi: 10.3389/fimmu.2017.00807

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Copyright © 2017 Deripapa, Balashov, Rodina, Laberko, Myakova, Davydova, Gordukova, Abramov, Pay, Shelikhova, Prodeus, Maschan, Maschan and Shcherbina.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Macroscopic and microscopic images of granulomatous lesion in a boy with Nijmegen Breakage Syndrome: (A) at referral, after multiple courses of antibiotics and topical steroids, (B) after conditioning for hematopoietic stem cell transplantation, (C) skin histology demonstrating perivascular and diffuse, mixed-cell infiltrate in superficial and deep dermis. H&E stain, 40× magnification, (D) skin histology demonstrating palisaded inflammatory infiltrates consisting of histocytes, lymphocytes, and neutrophils, associated with basophilic alterations of collagen. H&E stain, 400× magnification.