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. 2017 Jul 24;8:807. doi: 10.3389/fimmu.2017.00807

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Copyright © 2017 Deripapa, Balashov, Rodina, Laberko, Myakova, Davydova, Gordukova, Abramov, Pay, Shelikhova, Prodeus, Maschan, Maschan and Shcherbina.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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T-cell excision circle (TREC) and kappa-deleting recombination excision circle (KREC) levels in various groups of Nijmegen Breakage Syndrome (NBS) patients. (A,B) TREC and KREC levels in NBS patients with and without infection. (C,D) TREC and KREC levels in NBS patients with and without autoimmune complications. (E,F) TREC and KREC levels in NBS patients with and without malignancies. (G,H) Age-dependent distribution of TREC and KREC levels in NBS patients. Asterisk indicates statistically significant difference between the groups. TREC/KREC levels are expressed per 10⁵ cells. Note logarithmical scale of the graphs.