Table 1.
Baseline Characteristics, Hemodynamics, Arterial Blood Gas Analysis, and Timing and Incidence of ROSC in the 4 Study Groups
| Group 1 RA (n=11) | Group 2 UVC (n=11) | Group 3 Postcompression ETT (n=11) | Group 4 Precompression ETT (n=11) | |
|---|---|---|---|---|
| Weight, kg | 3.6±0.6 | 3.6±0.8 | 3.7±0.9 | 3.9±0.9 |
| Sex (M:F) | 7:4 | 5:6 | 6:5 | 5:6 |
| Total lung fluid drained, mL/kg | 13±3.5 | 15±2.6 | 15±6.7 | 18±3.8 |
| Hemoglobin, g/dL | 12.8±2.3 | 12±1.7 | 12.5±1.0 | 12.4±0.8 |
| Baseline hemodynamics | ||||
| Heart rate, bpm | 154±24 | 174±29 | 157±26 | 160±25 |
| SBP mean, mm Hg | 56±8.5 | 59±10 | 53±12 | 48±15 |
| DBP mean, mm Hg | 39±6.8 | 44±9.5 | 38±7.3 | 32±11 |
| Mean left carotid flow, mL/kg per minute | 26±7.1 | 32±8.5 | 25±8.7 | 27±8.8 |
| Baseline ABG | ||||
| pH | 7.22±0.11 | 7.10±0.09 | 7.15±0.08 | 7.16±0.14 |
| PaCO2, mm Hg | 64±15 | 67±7 | 69±11 | 68±7 |
| PaO2, mm Hg | 24±2.8 | 19±5.2 | 21±10 | 20±3.5 |
| SpO2, % | 64±7 | 54±12 | 61±20 | 57±8 |
| Lactate, mmol/L | 3.9±1.4 | 4.9±3.6 | 6.1±3.2 | 4.8±3.5 |
| Time to asystole, minute | 18 (16–21) | 14 (12–20) | 15 (14–16) | 14 (12–14) |
| ROSC | 10/11 (91%) | 9/11 (82%) |
8/11 (73%) After RA epi (9/11) |
4/11 (36%) After RA epi (10/11) |
| Time to ROSC, minute | 2 (1.6–2.9) | 2.5 (2–3) | 4 (2.9–4.8)a | 7 (3–8)b |
Data are mean±SD; time variables are median (interquartile ranges). ABG indicates arterial blood gas; bpm, beats per minute; DBP, diastolic blood pressure; epi, epinephrine; ETT, endotracheal tube; RA, right atrium; ROSC, return of spontaneous circulation; SBP, systolic blood pressure; SpO2, preductal arterial oxyhemoglobin saturation; UVC, umbilical venous catheter.
a
P<0.05 compared to group 1.
b
P<0.05 compared to group 1 and group 2.