Table 3.
Association Between Vascular Structure and Function Measures Among Siblings and Parent and Their Offspring
| Measure | Siblings (n=338) | Parent‐Offspring (n=477) | ||
|---|---|---|---|---|
| r | P Value | R | P Value | |
| Brachial artery diameter, mm | 0.14 | 0.012 | 0.11 | 0.021 |
| FMD, %a | 0.04 | 0.53 | 0.01 | 0.90 |
| cLD, mm | 0.31 | <0.001 | 0.22 | <0.001 |
| cIMT, mm | 0.11 | 0.052 | 0.08 | 0.073 |
| cIEM, mm Hg | 0.16 | 0.002 | 0.04 | 0.36 |
| cDD, % | 0.15 | 0.005 | 0.19 | <0.001 |
| cCSD, % | 0.15 | 0.005 | 0.19 | <0.001 |
| cDC, mm/mm Hg | −0.03 | 0.58 | 0.03 | 0.46 |
| cCSC, mm2/mm Hg | 0.21 | <0.001 | 0.14 | 0.015 |
| PWV, m/s | 0.24 | <0.001 | 0.14 | 0.018 |
Data are partial Pearson correlations adjusted for age, sex, race, BMI, MAP, and smoking of both participants. BMI indicates body‐mass index; cCSC, carotid cross‐sectional compliance; cCSD, carotid cross‐sectional distensibility; cDC, carotid diameter compliance; cDD, carotid diameter distensibility; cIEM, carotid incremental elastic modulus; cIMT, carotid intima media thickness; cLD, carotid lumen diameter; FMD, flow‐mediated dilation; MAP, mean arterial pressure; PWV, pulse wave velocity.
a
Denotes further adjustment for brachial artery diameter.