Table 1.
General Characteristics of Obese and Nonobese Children With and Without OSA
| Obese, No OSA (n=40) | Obese, OSA (n=40) | Nonobese, No OSA (n=40) | Nonobese, OSA (n=40) | |
|---|---|---|---|---|
| Age, y | 7.6±2.2 | 7.3±2.1 | 7.1±1.9 | 6.9±2.4 |
| Sex (male), % | 55.0 | 57.5 | 50.0 | 55.0 |
| Race (white), n | 6 | 6 | 12 | 10 |
| BMI z‐score | 2.28±0.11 | 2.37±0.42 | 0.21±0.80 | 0.07±0.88 |
| Systolic blood pressure, mm Hg | 115.1±9.4 | 122.2±9.6* | 106.8±8.7 | 111.8±8.6* |
| Diastolic blood pressure, mm Hg | 69.1±7.7 | 70.1±8.5* | 65.2±7.5 | 68.4±7.9 |
| Obstructive AHI, events/h | 0.91±0.22 | 18.3±14.6 | 0.48±0.30 | 18.3±13.6 |
| SpO2 nadir, % | 93.1±3.6 | 81.4±11.1 | 92.4±4.3 | 81.7±10.4 |
| Respiratory arousal index | 2.4±3.3 | 13.5±12.6 | 92.4±4.3 | 13.6±10.6 |
| LDL cholesterol, mg/dL | 91.1±24.9 | 101.5±26.2* | 85.7±15.1 | 91.9±19.7* |
| HDL cholesterol, mg/dL | 50.4±13.3 | 48.8±10.4 | 63.4±10.6 | 49.9±9.4* |
| Triglycerides, mg/dL | 90.7±50.2 | 96.0±48.9 | 74.8±32.3 | 75.5±31.1 |
| hsCRP, mg/L | 0.48±0.21 | 1.08±0.71* | 0.18±0.24 | 0.68±0.51* |
| Time to maximal hyperemic responses (Tmax), s | 40.5±8.5 | 49.5±8.8* | 29.9±6.5 | 42.1±9.6* |
| ED, n (%) | 6 (15%) | 26 (65%)* | 0 (0%) | 9 (22.5%)* |
| Lp‐PLA2 plasma activity, nmol/(min·mL) | 183.1±82.5 | 332.2±96.6* | 131.1±25.0 | 194.6±98.5* |
| Lp‐PLA2 plasma activity if ED present, nmol/(min·mL) | 334.7±47.2 | 390.4±64.5 | — | 338.2±93.8 |
| Lp‐PLA2 plasma activity if ED not present, nmol/(min·mL) | 156.3±52.7 | 224.1±26.0* | 131.1±25.0 | 152.8±47.7* |
BMI indicates body mass index; ED, endothelial dysfunction; HDL, high‐density lipid cholesterol; LDL, low‐density lipid cholesterol; Lp‐PLA2, lipoprotein‐associated phospholipase A2; SpO2, peripheral capillary oxygen saturation.
OSA vs no‐OSA: *P<0.05; ED=Tmax >45 s.