Table 1.
Characteristics of Patients Receiving methylene blue (MB) for vasoplegic syndrome
| Variable | MB | No MB | p-value |
|---|---|---|---|
| Number of patients | 118 (3.3%)1 | 3490 (96.7%) | - |
| Isolated Coronary Artery Bypass and/or Valve | 35 (29.6%) | 2381 (68.2) | <0.0001 |
| Ventricular Assist Device | 40 (33.9%) | 130 (3.7%%) | <0.0001 |
| Prior Ventricular Assist Device | 32 (27.1%) | 28 (0.1%) | <0.0001 |
| Age | 63 [58, 71]2 | 67 [57, 75] | 0.031 |
| Male Sex | 81 (69.2%) | 2334 (67.7%) | 0.720 |
| Tobacco Use | 46 (39.3%) | 785 (22.8%) | <0.0001 |
| Heart Failure Diagnosis | 88 (74.6%) | 1740 (49.9%) | <0.0001 |
| Dialysis Dependent Renal Failure | 7 (6.9%) | 94 (2.6%) | 0.036 |
| Diabetes Mellitus | 46 (39.0%) | 3488 (36.5%) | 0.586 |
| Severe Chronic Lung Disease | 10 (8.6%) | 143 (4.1%) | 0.008 |
| Hypertension | 77 (65.8%) | 2646 (76.7%) | 0.007 |
| Ejection Fraction | 42 [20, 58] | 57 [45, 63] | <0.0001 |
| Preoperative Amiodarone Therapy | 18 (15.3%) | 78 (2.2%) | <0.0001 |
| ACE-Inhibitor within 48 hours | 13 (11.0%) | 398 (11.4%) | 0.896 |
| Prior Cardiac Surgery | 89 (76.1%) | 1435 (41.2%) | <0.0001 |
| Cross Clamp Time | 100 [79, 126] | 75 [58, 96] | <0.0001 |
1
n (%), all such values
2
median [interquartile range], all such values