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Results of luciferase reporter assays of APP intronic fragment bearing rs2830077 SNP in HEK293FT cell line. On the left: Schematic drawing of the constructs used in the luciferase assay system. On the right: Corresponding transcription efficiency measurements, which were done in triplicates from 6 independent experiments. Results are expressed as a ratio of firefly to Renilla luciferase activity (means±SD) ***p < 0.001.
