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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: J Mol Cell Cardiol. 2017 May 2;108:8–16. doi: 10.1016/j.yjmcc.2017.04.005

Figure 4. 8-CPT and ISO-induced SR Ca2+ leak in rabbit myocytes.

Figure 4

The tetracaine-induced approach (Fig 2) was used to assess SR Ca2+ leak (Δ[Ca2+]SRT, bottom) in myocyte records with matched SR Ca2+ content ([Ca2+]SRT, top). SR Ca2+ leak induced by 10 μM 8-CPT was prevented by NOS inhibition (100 μM L-NAME; n= 18, 11, 11 myocytes; * p<0.05).