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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Atherosclerosis. 2017 May 12;262:131–137. doi: 10.1016/j.atherosclerosis.2017.05.014

Table 3.

ARIC visit 1 Lp(a) quintiles hazard ratios (95% CI) for incident heart failure hospitalization (prevalent and incident MI excluded).

Lp(a) [HF/at risk] Hazard ratio (95% confidence interval) p trend
Quintile 1
(0.02–2.28)
[295/2456 (12%)]		 Quintile 2
(2.41–5.46)
[294/2482 (12%)]		 Quintile 3
(5.59–11.03)
[329/2436 (14%)]		 Quintile 4
(11.16–22.43)
[356/2439 (15%)]		 Quintile 5
(22.57–107.60)
[356/2440 (15%)]
Model 1 reference 0.95
(0.81–1.12)		 1.00
(0.85–1.17)		 1.04
(0.88–1.22)		 0.99
(0.84–1.17)		 0.89
Model 2 reference 1.02
(0.87–1.20)		 1.07
(0.91–1.26)		 1.11
(0.94–1.31)		 1.07
(0.90–1.26)		 0.74
Model 3 reference 1.02
0.86–1.20)		 1.08
(0.92–1.27)		 1.12
(0.95–1.31)		 1.07
(0.91–1.27)		 0.70

Follow-up to December 31, 2012; mean follow-up 20.0±6.55 years, median follow-up 23.4 (16.8, 24.5) years. Lp(a) presented as mg/dL. p trend tests a linear increase in log relative hazard with increasing quintiles.

Models 1–3 are as described for Table 2.