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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Clin Chem. 2017 Apr 10;63(6):1083–1093. doi: 10.1373/clinchem.2016.262253

Figure 5.

Figure 5

Scheme for the simultaneous isolation of a free drug fraction and separation of the various chiral forms of a drug in this fraction by using ultrafast affinity extraction and an HPLC chiral stationary phase. This particular example uses an affinity microcolumn containing immobilized HSA for ultrafast affinity extraction. Reproduced from Ref. (73) with permission from The Royal Society of Chemistry.