Table 1.
IC50 values of ACGs-NSps, free FA+ACGs-NSps, and FA-ACGs-NSps against 4T1 and A549 cell lines after incubation for 24 hours
| Time | IC50 (μg/mL)
|
||
|---|---|---|---|
| Groups | 4T1 | A549 | |
| 24 h | ACGs-NSps | 0.352±0.037** | 7.083±0.890 |
| FA+ACGs-NSps | 0.379±0.037** | 7.449±0.999 | |
| FA-ACGs-NSps | 0.251±0.032 | 7.141±0.944 | |
Notes: Results are presented as mean ± SD; n=6.
**
P<0.01 versus FA-ACGs-NSps.
Abbreviations: ACGs-NSps, Annonaceous acetogenins nanosuspensions; FA, folic acid; FA+ACGs-NSps, the physical mixtures of FA and ACGs-NSps; FA-ACGs-NSps, FA-modified ACGs-NSps; IC50, 50% inhibitory concentration; SD, standard deviation.