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. 2017 Feb 27;6(3):e004694. doi: 10.1161/JAHA.116.004694

Figure 7.

Figure 7

Role of microRNA (miR)‐181a/b in the fundamental changes in cardiomyocyte contractility. A, Definitions for calcium (Ca2+) transient analysis. B, Representative sarcomere shortening and Ca2+ transients for miR‐181a/b−/− (a/b KO) mouse myocytes compared to wild type (WT) C57BL/6J adult myocytes. C, Quantification of peak amplitude of sarcomere shortening and Ca2+ transients, time to peak, time to 50% and 90% return to baseline measured with WT (n=20) and a/b KO (n=73‐75) mouse myocytes. Data are mean±SEM; *P<0.05; **P<0.01; ***P<0.001; ****P<0.0001.