Table 3.
Cardiovascular Events According to Estimated CVR (Framingham‐REGICOR Strategy) by Sex
| Low Risk | Moderate Risk | High Risk | Very High Risk | Total | |
|---|---|---|---|---|---|
| Women | |||||
| Participants, n (%) | 1236 (36.6) | 1527 (45.2) | 554 (16.4) | 58 (1.7) | 3375 (100) |
| Estimated CVR | 3.2±0.8 | 6.4±1.4 | 9.8±2.7 | 16.7±2.2 | 6.0±3.1 |
| MI, n | 1 | 14 | 5 | 2 | 22 |
| Events in risk strata, % | 0.1 | 0.9 | 0.9 | 3.5a | 0.7 |
| Total events, % | 4.6 | 63.6 | 22.7 | 9.1 | 100 |
| Stroke, n | 11 | 19 | 11 | 2 | 43 |
| Events in risk strata, % | 0.9 | 1.2 | 2.0 | 3.5 | 1.3 |
| Total events, % | 25.6 | 44.2 | 25.6 | 4.7 | 100 |
| CVD death, n | 5 | 7 | 1 | 1 | 14 |
| Events in risk strata, % | 0.4 | 0.5 | 0.2 | 1.7 | 0.4 |
| Total events, % | 35.7 | 50.0 | 7.14 | 7.14 | 100 |
| MACE, n | 14 | 38 | 15 | 3 | 70 |
| Events in risk strata, % | 1.1 | 2.5 | 2.7 | 5.2b | 2.1 |
| Total events, % | 20.0 | 54.3 | 21.4 | 4.3 | 100 |
| Expanded MACE, n | 22 | 54 | 31 | 3 | 110 |
| Events in risk strata, % | 1.8 | 3.5 | 5.6 | 5.2a | 3.3 |
| Total events, % | 20.0 | 49.1 | 28.2 | 2.7 | 100 |
| Men | |||||
| Participants, n (%) | 263 (10.2) | 1129 (43.6) | 782 (30.2) | 417 (16.1) | 2591 (100) |
| Estimated CV risk | 3.7±0.7 | 7.0±1.4 | 11.2±1.8 | 18.8±3.9 | 9.8±5.0 |
| MI, n | 0 | 20 | 21 | 11 | 52 |
| Events in risk strata, % | 0 | 1.8 | 2.7 | 2.6b | 2.0 |
| Total events, % | 0 | 38.5 | 40.4 | 21.1 | 100 |
| Stroke, n | 1 | 13 | 20 | 15 | 49 |
| Events in risk strata, % | 0.4 | 1.2 | 2.6 | 3.6a | 1.9 |
| Total events, % | 2.0 | 26.5 | 40.8 | 30.6 | 100 |
| CVD death, n | 0 | 8 | 10 | 16 | 34 |
| Events in risk strata, % | 0 | 0.7 | 1.3 | 3.8a | 1.3 |
| Total events, % | 0 | 23.5 | 29.4 | 47.1 | |
| MACE, n | 1 | 37 | 45 | 35 | 118 |
| Events in risk strata, % | 0.4 | 3.3 | 5.8 | 8.4a | 4.6 |
| Total events, % | 0.9 | 31.4 | 38.1 | 29.7 | 100 |
| Expanded MACE, n | 3 | 60 | 80 | 51 | 194 |
| Events in risk strata, % | 1.1 | 5.3 | 10.2 | 12.2a | 7.5 |
| Total events, % | 1.6 | 30.9 | 41.2 | 26.3 | 100 |
Data expressed as mean±SD or n (%) unless otherwise indicated. MACE is defined as MI, stroke, or cardiovascular death. Expanded MACE is MACE plus coronary revascularization or peripheral arterial disease. CVD indicates cardiovascular disease; CVR, cardiovascular risk; MACE, major adverse cardiac event; MI, myocardial infarction.
a
P<0.01 between groups.
b
P<0.05 between groups.