Table 3.
Multiple Regression Results for the Memory Neuropsychological Factor as a Function of SBP, BMI, and rCBF Areas
| Memory Factor | β | SE of β (95% CI) | P Value |
|---|---|---|---|
| Model 1 | |||
| SBP | −0.132 | 0.057 (−0.020 to −0.244) | 0.02 |
| Model 2 | |||
| SBP | −0.134 | 0.059 (−0.018 to −0.250) | 0.02 |
| BMI | −0.000 | 0.060 (0.118 to −0.118) | ns |
| SBP change, 2‐back | 0.042 | 0.058 (0.156 to −0.072) | ns |
| Model 3 | |||
| SBP | −0.120 | 0.058 (−0.006 to −0.234) | 0.04 |
| BMI | 0.006 | 0.059 (0.122 to −0.110) | ns |
| SBP change, 2‐back | 0.010 | 0.058 (0.124 to −0.104) | ns |
| Frontoparietal ROIs | 0.260 | 0.074 (0.405–0.115) | <0.001 |
| Frontostriatal ROIs | −0.169 | 0.079 (−0.014 to −0.324) | 0.03 |
Model 1 includes age, sex, race, and education as covariates with SBP. Model 2 adds BMI and SBP reactivity. Model 3 adds rCBF areas. Education and race were significant in all models; age was significant in model 1 only. Insular–subcortical ROIs did not contribute significantly in model 3. Model 1 R 2=0.311, model 2 R 2=0.313, model 3 R 2=0.357. BMI indicates body mass index; DBP, diastolic blood pressure; ns, not significant; rCBF, regional cerebral blood flow; ROI, region of interest; SBP, systolic blood pressure.