Table 4.
Multiple Regression Results for the Executive Function Neuropsychological Factor as a Function of SBP, BMI, and rCBF Areas
| Executive Function Factor | β | SE of β (95% CI) | P Value |
|---|---|---|---|
| Model 1 | |||
| SBP | −0.132 | 0.060 (−0.014 to −0.250) | 0.03 |
| Model 2 | |||
| SBP | −0.121 | 0.061 (−0.001 to −0.241) | <0.05 |
| BMI | −0.071 | 0.062 (0.051 to −0.193) | ns |
| SBP change, 2‐back | 0.099 | 0.061 (0.219 to −0.021) | ns |
| Model 3 | |||
| SBP | −0.118 | 0.060 (−0.000 to −0.236) | 0.05 |
| BMI | 0.098 | 0.062 (0.220 to −0.024) | ns |
| SBP change | 0.079 | 0.060 (0.200 to −0.039) | ns |
| Frontoparietal ROI's | 0.169 | 0.077 (0.320–0.018) | 0.03 |
Model 1 includes age, sex, race, and education as covariates with SBP. Model 2 adds BMI and SBP reactivity. Model 3 adds rCBF areas. Race was a significant effect in all models. Neither frontostriatal nor insular–subcortical ROIs were significantly related. Model 1 R 2=0.240, model 2 R 2=0.254, model 3 R 2=0.294. BMI indicates body mass index; DBP, diastolic blood pressure; ns, not significant; rCBF, regional cerebral blood flow; ROI, region of interest; SBP, systolic blood pressure.