Table 6.
Multiple Regression Results for Accuracy of Working Memory in the 2‐Back Task as a Function of SBP, BMI, and rCBF Areas
| 2‐Back Task Accuracy | β | SE of β (95% CI) | P Value |
|---|---|---|---|
| Model 1 | |||
| SBP | 0.127 | 0.060 (0.245–0.009) | 0.04 |
| Model 2 | |||
| SBP | 0.106 | 0.060 (0.224 to −0.012) | 0.08 |
| BMI | 0.033 | 0.061 (0.153 to −0.079) | ns |
| SBP reactivity | 0.247 | 0.060 (0.365–0.129) | <0.001 |
| Model 3 | |||
| SBP | 0.117 | 0.060 (0.235 to −0.001) | 0.05 |
| BMI | 0.039 | 0.060 (0.157 to −0.079) | ns |
| SBP reactivity | 0.226 | 0.060 (0.344–0.108) | <0.001 |
| Frontoparietal ROIs | 0.181 | 0.077 (0.332–0.030) | 0.02 |
Model 1 includes age, sex, race, and education as covariates with SBP. Model 2 adds BMI and SBP reactivity. Model 3 adds rCBF areas. Race and education were related significantly to 2‐back task accuracy in all models. Neither the frontostriatal nor insular–subcortical ROIs contributed significantly to model 3. Model 1 R 2=0.221, model 2 R 2=0.278, model 3 R 2=0.297. BMI indicates body mass index; DBP, diastolic blood pressure; ns, not significant; rCBF, regional cerebral blood flow; ROI, region of interest; SBP, systolic blood pressure.