Table 2.
TTR Across eGFR Strata
| All | eGFR ≥60 | eGFR 45 to 59 | eGFR 30 to 44 | eGFR <30 or Dialysis | P Value | |
|---|---|---|---|---|---|---|
| N | 7738 | 5692 | 1353 | 512 | 181 | |
| TTR %, median (IQR) | 83 (71–92) | 83 (71–92) | 83 (72–91) | 82 (68–90) | 70 (50–82) | <0.001 |
| TTR %, mean (SD) | 78 (20) | 78 (20) | 79 (19) | 76 (21) | 66 (23) | <0.001 |
| TTR in categories | ||||||
| TTR >75%, n (%) | 5204 (67.3) | 3853 (67.7) | 951 (70.3) | 324 (63.3) | 76 (42.0) | <0.001 |
| TTR 60% to 75%, n (%) | 1423 (18.4) | 1042 (18.3) | 248 (18.3) | 94 (18.4) | 39 (21.5) | |
| TTR <60%, n (%) | 1111 (14.4) | 797 (14.0) | 154 (11.4) | 94 (18.4) | 66 (36.5) | |
| Number of INR measurements, median (IQR) | 21 (9–39) | 20 (9–38) | 25 (10–41) | 24 (11–42) | 21 (9–43) | <0.001 |
| Median (IQR) days on warfarin | 254 (91–691) | 244 (91–671) | 329 (99–708) | 287 (96–704) | 175 (57–589) | <0.001 |
| Median (IQR) days between INRs | 12 (8–17) | 12 (8–17) | 13 (8–17) | 12 (8–16) | 9 (5–14) | <0.001 |
| Percent (IQR) of INRs >3.0 | 11% (0–19) | 11 (0–19) | 12 (3.7–20) | 13 (5.8–21) | 14 (6.5–23) | <0.001 |
| Percent (IQR) of INRs <2.0 | 19% (9–31) | 18 (9–30) | 19 (10–30) | 20 (10–31) | 29 (18–43) | <0.001 |
IQR indicates interquartile range; INRs, international normalized ratios; TTR, time‐in‐therapeutic range.