Table 3.
Predictors of TTR
| CKD Stagea (mL/min per 1.73 m2) | TTR (95% CI) | P Value | Change in TTR (95% CI) | P Value |
|---|---|---|---|---|
| ≥60 | 78% (77–79) | <0.001 | (Ref) | ··· |
| 45 to 59 | 79% (78–80) | <0.001 | 1% (0–25) | 0.033 |
| 30 to 44 | 77% (75–79) | <0.001 | −1% (−3 to 10) | 0.313 |
| <30 or dialysis | 68% (65–72) | <0.001 | −10% (−13 to −60) | <0.001 |
Simplified fractional regression analysis showing the mean predicted TTR across renal function categories and the relative change (in proportion) from the reference category.
a
Fractional regression analysis adjusted for: age (in categories: <65, 65–74, 75–85, ≥85 years), sex, diabetes mellitus, liver disease, hypertension, vascular disease (myocardial infarction, ischemic heart disease, peripheral arterial disease), heart failure, valvular disease, amiodarone use, aspirin use, and cancer. CKD indicates chronic kidney disease; TTR, time‐in‐therapeutic range.