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. 2017 Mar 8;6(3):e005247. doi: 10.1161/JAHA.116.005247

Figure 5.

Figure 5

Primary outcome according to the proportion of visits in which blood pressure was <140/90 mm Hg (≥25% vs <25%) (A) or time‐averaged systolic blood pressure (SBP) during the treatment period (120 to <140 mm Hg vs ≥140 mm Hg) (B) in various subgroups. Adjusted for age, sex, study centers, methylenetetrahydrofolate reductase C677T polymorphism, study treatment groups, body mass index, smoking, alcohol drinking, SBP and DBP, estimated glomerular filtration rate, fasting glucose, total cholesterol, folate, vitamin B12, and homocysteine levels at baseline. HR indicates hazard ratio; ISH, isolated systolic hypertension; SDH, systolic‐diastolic hypertension.