Table 5.
Long‐Term All‐Cause Mortality Stratified by Prior XRT Exposure, Separated by Relevant Subgroups
| Variable | XRT Group (n=172) | Comparison Group (n=172) |
|---|---|---|
| Age, median 65 y | ||
| <65 y | 34/92 (37) | 0/83 |
| ≥65 y | 49/80 (61) | 12/89 (14) |
| Sex | ||
| Male | 28/66 (42) | 2/66 (3) |
| Female | 35/106 (33) | 10/106 (9) |
| Obstructive coronary artery disease | ||
| Yes | 57/127 (45) | 7/125 (6) |
| No | 26/45 (58) | 5/47 (11) |
| Left ventricular stroke volume index | ||
| <35 mL/m2 | 46/89 (52) | 6/61 (10) |
| ≥35 mL/m2 | 37/83 (45) | 6/111 (5) |
| Society of Thoracic Surgeons score, median 4% | ||
| <4% | 30/78 (39) | 0/91 |
| ≥4% | 53/94 (56) | 12/81 (15) |
| Surgery | ||
| AVR | 10/40 (25) | 7/94 (7) |
| AVR+CABG | 26/45 (58) | 5/47 (11) |
| AVR+aorta | 47/87 (54) | 0/91 |
| Redo cardiac surgery | ||
| No | 54/138 (39) | 9/143 (6) |
| Yes | 28/34 (82) | 3/29 (10) |
| AVR type | ||
| Bioprosthetic | 71/127 (52) | 12/157 (8) |
| Mechanical | 12/35 (34) | 0/15 |
| Permanent postoperative atrial fibrillation | ||
| No | 55/123 (45) | 10/148 (7) |
| Yes | 28/49 (57) | 2/24 (8) |
All differences between subgroups were significant (P<0.001), derived from univariable Cox proportional hazard analysis, shown in Table 3. Values are expressed as number (percentage) AVR indicates aortic valve replacement; CABG, coronary artery bypass grafting; XRT, chest radiotherapy.