Figure 3. Flurothyl-induced seizure behaviors in C57BL6/J mice during 8 induction phase seizures, and a final flurothyl rechallenge (retest) after a 28-day incubation phase.

While none of the C57BL6/J mice expressed a complex forebrain→brainstem seizure during the flurothyl induction trials (these mice only expressed clonic-forebrain seizures), 75-100% of C57BL6/J mice will express forebrain→brainstem seizures following a rechallenge to flurothyl following a 28-day incubation period.