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. 2017 Jun 5;7(11):e2309. doi: 10.21769/BioProtoc.2309

Table 1. Behavioral seizure classification grading scale.

Seizure grade Description of corresponding seizure behavior*
Grade 1 Loss of posture associated with facial clonus, including chewing, and clonus of forelimbs and/or hindlimbs
Grade 2 Grade 1 seizure followed by recovery of the righting reflex and low intensity bouncing
Grade 3 Grade 1 and/or 2 features with recovery of the righting reflex followed by wild running and popcorning
Grade 4 Grade 3 followed by forelimb and/or hindlimb treading
Grade 5 Grades 3 and/or 4 followed by bilateral tonic extension of the forelimbs
Grade 6 Grade 5 followed by bilateral tonic extension of the hindlimbs
Grade 7 Grade 6 followed by immediate death