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Basolateral to apical flux (Papp) of a 3H-IgG and FITC-dextran across rat and human FcRn over-expressing MDCK cells and EV cells. The highest Papp was observed in the cell line over-expressing FcRn and under pH 6.0/8.0, indicating a specific FcRn-mediated antibody transport. Data is shown as mean ± SD; n = 3 (separate wells).
